Rabbit monoclonal antibody (RabMAb) demonstrates larger sensitivity with out sacrificing specificity than mouse monoclonal antibody (MMAb). MMAb towards E-cadherin stain is closely utilized in distinguishing ductal carcinoma in situ (DCIS) from lobular carcinoma in situ (LCIS). We aimed to check the E-cadherin stain utilizing RabMAb vs MMAb in distinguishing DCIS from LCIS.
One hundred and seventeen in situ breast carcinomas (55 DCIS, 58 LCIS, and four DCIS and LCIS) have been studied. Sections from a consultant block of every have been stained with RabMAb [EP700Y] and MMAb [36B5]. Scanned photos of stained slides have been in contrast in tandem.
All DCIS instances (59/59) confirmed comparable staining by RabMAb and MMAb. Comparable staining was additionally noticed in all however one case of LCIS (61/62; 98%).
One case of pleomorphic LCIS confirmed principally full, weak to reasonably intense membranous staining with RabMAb and fragmented, weak membranous staining with MMAb.
NFAT Inhibitor |
A4539-1 |
ApexBio |
1 mg |
EUR 138 |
Description: Selective inhibitor of calcineurin-mediated dephosphorylation of nuclear factor of activated T cells (NFAT). Does not disrupt other calcineurin-dependent pathways. Inhibits NFAT activation and NFAT-dependent expression of endogenous cytokine genes in T cells. |
NFAT Inhibitor |
A4539-10 |
ApexBio |
10 mg |
EUR 763 |
Description: Selective inhibitor of calcineurin-mediated dephosphorylation of nuclear factor of activated T cells (NFAT). Does not disrupt other calcineurin-dependent pathways. Inhibits NFAT activation and NFAT-dependent expression of endogenous cytokine genes in T cells. |
NFAT Inhibitor |
A4539-5 |
ApexBio |
5 mg |
EUR 450 |
Description: Selective inhibitor of calcineurin-mediated dephosphorylation of nuclear factor of activated T cells (NFAT). Does not disrupt other calcineurin-dependent pathways. Inhibits NFAT activation and NFAT-dependent expression of endogenous cytokine genes in T cells. |
pGreenFire1-4x-NFAT (plasmid) |
TR051pa-1 |
SBI |
10 ug |
EUR 786 |
- Category: Lentiviral Technology
|
pGreenFire1-4x-NFAT (virus) |
TR051va-1 |
SBI |
>2 x 10^6 IFUs |
EUR 786 |
- Category: Lentiviral Technology
|
pGreenFire 2.0 NFAT reporter plasmid (pGF2-NFAT-rFluc-T2A-GFP-mPGK-Puro) |
TR451PA-P |
SBI |
10 µg |
EUR 767 |
- Category: Lentiviral Technology / Reporters
|
pGreenFire 2.0 NFAT reporter virus (pGF2-NFAT-rFluc-T2A-GFP-mPGK-Puro) |
TR451VA-P |
SBI |
>2 x 10^6 IFUs |
EUR 767 |
- Category: Lentiviral Technology / Reporters
|
NFAT Transcription Factor Regulator-1 |
HY-112778 |
MedChemExpress |
100mg |
EUR 3206 |
Human NFAT activation molecule 1 (NFAM1) ELISA Kit |
abx520337-96tests |
Abbexa |
96 tests |
EUR 668 |
- Shipped within 5-12 working days.
|
ELISA kit for Mouse NFAT activation molecule 1 |
EK4618 |
SAB |
96 tests |
EUR 603 |
Description: Enzyme-linked immunosorbent assay kit for quantification of Mouse NFAT activation molecule 1 in samples from serum, plasma, tissue homogenates and other biological fluids. |
Mouse Nfam1/ NFAT activation molecule 1 ELISA Kit |
E1020Mo |
Sunlong |
1 Kit |
EUR 632 |
Human NFAM1/ NFAT activation molecule 1 ELISA Kit |
E1735Hu |
Sunlong |
1 Kit |
EUR 605 |
Human NFAT activation molecule 1, NFAM1 ELISA KIT |
ELI-36505h |
Lifescience Market |
96 Tests |
EUR 824 |
Mouse NFAT activation molecule 1, Nfam1 ELISA KIT |
ELI-38266m |
Lifescience Market |
96 Tests |
EUR 865 |
Mouse Nfam1(NFAT activation molecule 1) ELISA Kit |
EM0772 |
FN Test |
96T |
EUR 567.6 |
- Detection range: 0.156-10 ng/ml
- Uniprot ID: Q8R4V1
- Alias: Nfam1/Cnaip/NFAT activation molecule 1/Calcineurin/NFAT-activating ITAM-containing protein/NFAT-activating protein with ITAM motif 1
|
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Mus ;Sensitivity: 0.094 ng/ml |
Mouse NFAT activation molecule 1 (NFAM1) ELISA Kit |
abx255120-96tests |
Abbexa |
96 tests |
EUR 668 |
- Shipped within 5-12 working days.
|
NFAT Activating Protein With ITAM Motif 1 (NFAM1) Antibody |
20-abx217148 |
Abbexa |
|
|
- Shipped within 5-10 working days.
|
NFAT Activating Protein With ITAM Motif 1 (NFAM1) Antibody |
abx235689-100ug |
Abbexa |
100 ug |
EUR 551 |
- Shipped within 5-12 working days.
|
NFAT Activating Protein With ITAM Motif 1 (NFAM1) Antibody |
20-abx301606 |
Abbexa |
-
EUR 411.00
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EUR 1845.00
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EUR 599.00
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EUR 182.00
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EUR 300.00
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100 ug
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1 mg
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200 ug
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20 ug
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50 ug
|
- Shipped within 5-10 working days.
|
Nfam1 ELISA Kit| Mouse NFAT activation molecule 1 ELISA Kit |
EF013382 |
Lifescience Market |
96 Tests |
EUR 689 |
NFAT Activating Protein With ITAM Motif 1 (NFAM1) Antibody (HRP) |
20-abx310130 |
Abbexa |
-
EUR 411.00
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EUR 1845.00
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EUR 599.00
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EUR 182.00
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EUR 300.00
|
-
100 ug
-
1 mg
-
200 ug
-
20 ug
-
50 ug
|
- Shipped within 5-10 working days.
|
NFAT Activating Protein With ITAM Motif 1 (NFAM1) Antibody (FITC) |
20-abx310131 |
Abbexa |
-
EUR 411.00
-
EUR 1845.00
-
EUR 599.00
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EUR 182.00
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EUR 300.00
|
-
100 ug
-
1 mg
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200 ug
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20 ug
-
50 ug
|
- Shipped within 5-10 working days.
|
NFAT Activating Protein With ITAM Motif 1 (NFAM1) Antibody (Biotin) |
20-abx310132 |
Abbexa |
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EUR 411.00
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EUR 1845.00
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EUR 599.00
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EUR 182.00
-
EUR 300.00
|
-
100 ug
-
1 mg
-
200 ug
-
20 ug
-
50 ug
|
- Shipped within 5-10 working days.
|
Consistently higher staining high quality was noticed in slides stained by RabMAb vs MMAb. RabMAb and MMAb towards E-cadherin have been diagnostically equal aside from one case the place RabMAb might have led to diagnostic misinterpretation.
However, the not insignificant value financial savings and simpler interpretation utilizing RabMAb might justify the chance of misinterpretation of elevated staining in uncommon instances, largely avertable with correct coaching.