Rabbit monoclonal E-cadherin antibody: A cost-effective alternative to mouse monoclonal antibody in distinguishing ductal carcinoma in situ from lobular carcinoma in situ.

Rabbit monoclonal antibody (RabMAb) demonstrates larger sensitivity with out sacrificing specificity than mouse monoclonal antibody (MMAb). MMAb towards E-cadherin stain is closely utilized in distinguishing ductal carcinoma in situ (DCIS) from lobular carcinoma in situ (LCIS). We aimed to check the E-cadherin stain utilizing RabMAb vs MMAb in distinguishing DCIS from LCIS.

One hundred and seventeen in situ breast carcinomas (55 DCIS, 58 LCIS, and four DCIS and LCIS) have been studied. Sections from a consultant block of every have been stained with RabMAb [EP700Y] and MMAb [36B5]. Scanned photos of stained slides have been in contrast in tandem.

All DCIS instances (59/59) confirmed comparable staining by RabMAb and MMAb. Comparable staining was additionally noticed in all however one case of LCIS (61/62; 98%).

One case of pleomorphic LCIS confirmed principally full, weak to reasonably intense membranous staining with RabMAb and fragmented, weak membranous staining with MMAb.

NFAT Inhibitor
H-4874.0500	Bachem	0.5mg	EUR 327.6
Description: Sum Formula: C75H118N20O22S; CAS# [249537-73-3] net

NFAT Inhibitor
H-4874.1000	Bachem	1.0mg	EUR 544.8
Description: Sum Formula: C75H118N20O22S; CAS# [249537-73-3] net

pGreenFire1-4x-NFAT (plasmid)
TR051pa-1	SBI	10 ug	EUR 943.2

pGreenFire1-4x-NFAT (virus)
TR051va-1	SBI	>2 x 10^6 IFUs	EUR 943.2

NFAT eGFP Reporter Lentivirus
79922	BPS Bioscience	500 µl x 2	EUR 875
Description: The NFAT eGFP Reporter Lentivirus are replication incompetent, HIV-based, VSV-G pseudotyped lentiviral particles that are ready to be transduced into almost all types of mammalian cells, including primary and non-dividing cells. The particles contain an enhanced GFP gene driven by the NFAT response element located upstream of the minimal TATA promoter. After transduction, activation of the NFAT signaling pathway in the target cells can be monitored by examining eGFP expression._x000D_

pGreenFire 2.0 NFAT reporter plasmid (pGF2-NFAT-rFluc-T2A-GFP-mPGK-Puro)
TR451PA-P	SBI	10 µg	EUR 920.4

pGreenFire 2.0 NFAT reporter virus (pGF2-NFAT-rFluc-T2A-GFP-mPGK-Puro)
TR451VA-P	SBI	>2 x 10^6 IFUs	EUR 920.4

NFAT Transcription Factor Regulator-1
HY-112778	MedChemExpress	100mg	EUR 3847.2

pGL4.30[luc2P- NFAT- RE- Hygro]
PVT10800	Lifescience Market	2 ug	EUR 361.2

NFAT Luciferase-RFP Reporter Lentivirus
78617-H	BPS Bioscience	500 µl x 2	EUR 835
Description: The NFAT Luciferase-RFP Reporter Lentiviruses are replication incompetent, HIV-based, VSV-G pseudotyped lentiviral particles that are ready to transduce almost all types of mammalian cells, including primary and non-dividing cells. The particles contain a firefly luciferase and RFP (Red Fluorescent Protein) cassette driven by the NFAT response element located upstream of the minimal TATA promoter and a hygromycin or puromycin selection gene to generate stable clones. After transduction, activation of the NFAT signaling pathway in the target cells can be monitored by measuring the luciferase activity or RFP expression. RFP fluoresces red-orange when excited; it has an excitation wavelength of 553 nm, and an emission wavelength of 574 nm.

NFAT Luciferase-RFP Reporter Lentivirus
78617-P	BPS Bioscience	500 µl x 2	EUR 835
Description: The NFAT Luciferase-RFP Reporter Lentiviruses are replication incompetent, HIV-based, VSV-G pseudotyped lentiviral particles that are ready to transduce almost all types of mammalian cells, including primary and non-dividing cells. The particles contain a firefly luciferase and RFP (Red Fluorescent Protein) cassette driven by the NFAT response element located upstream of the minimal TATA promoter and a hygromycin or puromycin selection gene to generate stable clones. After transduction, activation of the NFAT signaling pathway in the target cells can be monitored by measuring the luciferase activity or RFP expression. RFP fluoresces red-orange when excited; it has an excitation wavelength of 553 nm, and an emission wavelength of 574 nm.

pCDH-NFAT-Luc2-T2A-tdTomato Plasmid
PVT16080	Lifescience Market	2 ug	EUR 390

TIGIT / NFAT Reporter - Jurkat Cell Line
60538	BPS Bioscience	2 vials	EUR 10855
Description: Recombinant Jurkat cell line constitutively expressing a full length human TIGIT (T_x000D_cell Immunoreceptor with Immunoglobulin and ITIM domain; VSTM3), and a firefly luciferase_x000D_gene under the control of nuclear factor of activator T cells (NFAT) response element. Both_x000D_TIGIT and NFAT constructs have been stably integrated into Jurkat cells. TIGIT expression has_x000D_been confirmed by Western Blot, and TIGIT-specific NFAT response has been validated using a_x000D_TIGIT ligand, CD155 (PVR).

NFAT Reporter (Luc) - Jurkat Cell Line
60621	BPS Bioscience	2 vials	EUR 2295
Description: The NFAT Reporter - Jurkat Cell Line contains a firefly luciferase gene under the control of the_x000D_NFAT response element stably integrated into Jurkat cells. This cell line has been validated for_x000D_response to thapsigargin, ionomycin, and phorbol 12-myristate 13-acetate (PMA). It is useful as_x000D_a control cell line for other NFAT reporter cell lines expressing various immune checkpoint_x000D_receptors.

NFAT Luciferase Reporter Lentivirus-79579-G
79579-G	BPS Bioscience	500 µl x 2	EUR 835
Description: The NFAT Luciferase Reporter Lentiviruses are replication incompetent, HIV-based, VSV-G pseudotyped lentiviral particles that are ready to transduce almost all types of mammalian cells, including primary and non-dividing cells. The particles contain a firefly luciferase gene driven by the NFAT response element located upstream of the minimal TATA promoter (Figure 1) and an antibiotic selection gene (hygromycin, puromycin, or G418) for the selection of stable clones. After transduction, activation of the NFAT signaling pathway in the target cells can be monitored by measuring the luciferase activity.

NFAT Luciferase Reporter Lentivirus-79579-H
79579-H	BPS Bioscience	500 µl x 2	EUR 860
Description: The NFAT Luciferase Reporter Lentiviruses are replication incompetent, HIV-based, VSV-G pseudotyped lentiviral particles that are ready to transduce almost all types of mammalian cells, including primary and non-dividing cells. The particles contain a firefly luciferase gene driven by the NFAT response element located upstream of the minimal TATA promoter and an antibiotic selection gene (hygromycin or puromycin) for the selection of stable clones. After transduction, activation of the NFAT signaling pathway in the target cells can be monitored by measuring the luciferase activity.

NFAT Luciferase Reporter Lentivirus-79579-P
79579-P	BPS Bioscience	500 µl x 2	EUR 860
Description: The NFAT Luciferase Reporter Lentiviruses are replication incompetent, HIV-based, VSV-G pseudotyped lentiviral particles that are ready to transduce almost all types of mammalian cells, including primary and non-dividing cells. The particles contain a firefly luciferase gene driven by the NFAT response element located upstream of the minimal TATA promoter and an antibiotic selection gene (hygromycin or puromycin) for the selection of stable clones. After transduction, activation of the NFAT signaling pathway in the target cells can be monitored by measuring the luciferase activity.

PD-1 / NFAT Reporter - Jurkat Cell Line
60535	BPS Bioscience	2 vials	EUR 11375
Description: Recombinant Jurkat T cell expressing firefly luciferase gene under the control of NFAT response elements with constitutive expression of human PD-1 (Programmed Cell Death 1, PDCD1, SLEB2, CD279, GenBank Accession #NM_005018)._x000D_

NFAT Reporter (Luciferase) - THP-1 Cell Line
78320	BPS Bioscience	2 vials	EUR 1810
Description: The NFAT reporter (Luciferase)-THP-1 cell line is designed for monitoring the NFAT (nuclear factor of activated T-cells) signaling pathway in THP-1 cells by measuring luciferase activity. It contains a firefly luciferase gene driven by the NFAT response element located upstream of the minimal TATA promoter. Upon activation by NFAT activators such as Ionomycin, endogenous NFAT transcription factors bind to the DNA response elements, inducing transcription of the luciferase reporter gene.

TMIGD2/NFAT Luciferase Reporter Jurkat Cell Line
78323	BPS Bioscience	2 vials	EUR 10340
Description: Recombinant Jurkat cell line expressing firefly luciferase under the control of an NFAT response element, and with constitutive expression of human TMIGD2 (Transmembrane and immunoglobulin domain containing 2; CD28H; NM_144615). Expression of the firefly luciferase gene is driven by NFAT response elements located upstream of the minimal TATA promoter. Activation of the NFAT signaling pathway in these cells can be monitored by measuring luciferase activity.

NFAT Reporter (eGFP) Jurkat Recombinant Cell Line
78384	BPS Bioscience	2 vials	EUR 2240
Description: Recombinant Jurkat T-cells expressing an enhanced GFP (eGFP) gene under the control of NFAT response elements located upstream of the minimal TATA promoter. Activation of the NFAT signaling pathway can be monitored by examining eGFP expression.

NFAT Luciferase-eGFP Reporter Lentivirus-78656-G
78656-G	BPS Bioscience	500 µl x 2	EUR 835
Description: The NFAT Luciferase-eGFP Reporter Lentiviruses are replication incompetent, HIV-based, VSV-G pseudotyped lentiviral particles that are ready to transduce almost all types of mammalian cells, including primary and non-dividing cells. The particles contain a firefly luciferase and eGFP cassette driven by the NFAT response element located upstream of the minimal TATA promoter (Figure 1) and a puromycin selection gene to generate stable clones. After transduction, activation of the NFAT signaling pathway in the target cells can be monitored by measuring the luciferase activity or eGFP expression.

NFAT Luciferase-eGFP Reporter Lentivirus-78656-P
78656-P	BPS Bioscience	500 µl x 2	EUR 835
Description: The NFAT Luciferase-eGFP Reporter Lentiviruses are replication incompetent, HIV-based, VSV-G pseudotyped lentiviral particles that are ready to transduce almost all types of mammalian cells, including primary and non-dividing cells. The particles contain a firefly luciferase and eGFP cassette driven by the NFAT response element located upstream of the minimal TATA promoter (Figure 1) and a puromycin selection gene to generate stable clones. After transduction, activation of the NFAT signaling pathway in the target cells can be monitored by measuring the luciferase activity or eGFP expression.

NFAT Luciferase-eGFP Reporter Jurkat Cell Line
78662	BPS Bioscience	2 vials	EUR 2195
Description: Recombinant Jurkat T cells expressing both firefly luciferase and enhanced GFP (eGFP) under the control of NFAT response elements located upstream of the minimal TATA promoter. Activation of the NFAT signaling pathway can be monitored by examining either firefly luciferase or eGFP expression.

VEGFR2 / NFAT Reporter - HEK293 Recombinant Cell Line
79387	BPS Bioscience	2 vials	EUR 12205
Description: Recombinant HEK-293 cells expressing firefly luciferase gene under the control of NFAT response elements with constitutive expression of human VEGFR2 (Human Vascular Endothelial Growth Factor Receptor 2; KDR, FLK1; ref seq. NM_002253.1).

ICOS/NFAT Reporter-Jurkat Recombinant Cell Line
79668	BPS Bioscience	2 vials	EUR 10340
Description: Recombinant Jurkat T cell expressing firefly luciferase gene under the control of NFAT response elements with constitutive expression of a chimeric receptor consisting human ICOS (also known as inducible T-cell costimulator or CD278, Genbank Accession #NM_012092) and the cytoplasmic domain of human CD3 zeta._x000D_

Mouse Nfam1/ NFAT activation molecule 1 ELISA Kit
E1020Mo	Sunlong	1 Kit	EUR 758.4

Human NFAM1/ NFAT activation molecule 1 ELISA Kit
E1735Hu	Sunlong	1 Kit	EUR 726

Mouse Nfam1(NFAT activation molecule 1) ELISA Kit
EM0772	FN Test	96T	EUR 681.12
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Mus ;Sensitivity: 0.094 ng/ml

ELISA kit for Mouse NFAT activation molecule 1
EK4618	SAB	96 tests	EUR 723.6
Description: Enzyme-linked immunosorbent assay kit for quantification of Mouse NFAT activation molecule 1 in samples from serum, plasma, tissue homogenates and other biological fluids.

Human NFAT activation molecule 1 (NFAM1) ELISA Kit
abx520337-96tests	Abbexa	96 tests	EUR 801.6

Mouse NFAT activation molecule 1 (NFAM1) ELISA Kit
abx255120-96tests	Abbexa	96 tests	EUR 801.6

Mouse NFAT activation molecule 1, Nfam1 ELISA KIT
ELI-38266m	Lifescience Market	96 Tests	EUR 1038

Human NFAT activation molecule 1, NFAM1 ELISA KIT
ELI-36505h	Lifescience Market	96 Tests	EUR 988.8

LAG-3 / NFAT Reporter - Jurkat Recombinant Cell Line
71278	BPS Bioscience	2 vials	EUR 11095
Description: Recombinant Jurkat T cell expressing firefly luciferase gene under the control of NFAT response elements with constitutive expression of human LAG-3 (lymphocyte-activation gene 3, CD223, GenBank Accession # NM_002286).

B2M Knockout NFAT Luciferase Reporter Jurkat Cell Line
78363	BPS Bioscience	2 vials	EUR 11095
Description: B2M (Beta-2-Microglobulin) has been genetically removed by CRISPR/Cas9 genome editing from NFAT Luciferase Reporter Jurkat cells. Expression of the firefly luciferase gene is driven by NFAT response elements located upstream of the minimal TATA promoter. Activation of the NFAT signaling pathway in these cells can be monitored by measuring luciferase activity.

TCR Knockout NFAT-Luciferase Reporter Jurkat Cell Line
78556	BPS Bioscience	2 vials	EUR 12205
Description: This cell line is a knockout of TCR (T Cell Receptor). The TRAC (T-Cell Receptor Alpha Constant) and TRBC1 (T-Cell Receptor Beta Constant 1) domains of the TCRα/β chains were genetically removed by CRISPR/Cas9 genome editing from recombinant Jurkat cells stably expressing the firefly luciferase gene under the control of NFAT response elements.This cell line has been functionally validated and does not respond to anti-CD3 agonist antibodies, as opposed to parental NFAT-Luciferase Reporter Jurkat cells (BPS Bioscience #60621).

NFAT Reporter - Hek293 Cell Line (PKC/ Ca2+ Pathway)
79298	BPS Bioscience	2 vials	EUR 2140
Description: The NFAT Reporter - Hek293 cell line contains a firefly luciferase gene under the control of NFAT response element stably integrated into Hek293 cells. This cell line is validated for the response to the stimulation of phorbol 12-myristate 13-acetate (PMA) with ionomycin.

CD160/NFAT - Luciferase Reporter - Jurkat Recombinant Cell Line
79594	BPS Bioscience	2 vials	EUR 9400
Description: Recombinant Jurkat T cell expressing firefly luciferase gene under the control of NFAT response elements with constitutive expression of human CD160. CD160 is a GPIanchored glycoprotein member of the Ig superfamily, also known as BY55, NK1, and NK28. GenBank Accession # NM_007053._x000D__x000D_

LILRB4 NFAT-Luciferase Reporter Jurkat Recombinant Cell Line
79750	BPS Bioscience	2 vials	EUR 9870
Description: Recombinant Jurkat cells constitutively expressing human LILRB4 (Leukocyte Immunoglobulin-Like Receptor Subfamily B Member 4, GenBank Accession #NM_001278426) and the firefly luciferase gene under the control of NFAT response elements.

NFAT Activating Protein With ITAM Motif 1 (NFAM1) Antibody
20-abx301606	Abbexa	EUR 493.20 EUR 2214.00 EUR 718.80 EUR 218.40 EUR 360.00	100 ug 1 mg 200 ug 20 ug 50 ug

NFAT Activating Protein With ITAM Motif 1 (NFAM1) Antibody
20-abx217148	Abbexa	EUR 510.00 EUR 410.40	100 ug 50 ug

NFAT Activating Protein With ITAM Motif 1 (NFAM1) Antibody
abx235689-100ug	Abbexa	100 ug	EUR 661.2

TCR/B2M Knockout NFAT Luciferase Reporter Jurkat Cell Line
78557	BPS Bioscience	2 vials	EUR 16695
Description: This cell line is a double knockout of TCR (T Cell Receptor) and B2M (Beta-2-Microglobulin). First, the TRAC (T-Cell Receptor Alpha Constant) and the TRBC1 (T-Cell Receptor Beta Constant 1) domains of the TCRα/β chains were genetically removed by CRISPR/Cas9 genome editing from NFAT Luciferase Reporter Jurkat cells to generate the TCR Knockout NFAT Luciferase Reporter Jurkat cell Line (BPS Bioscience #78556). These TCR knockout cells were used to generate a new cell line in which B2M was also genetically removed by CRISPR/Cas9 genome editing. _x000D_Expression of the firefly luciferase gene is driven by NFAT response elements located upstream of the minimal TATA promoter. Activation of the NFAT signaling pathway in these cells can be monitored by measuring luciferase activity.

Woodchuck PD-1 / NFAT - Reporter - Jurkat Recombinant Cell Line
79456	BPS Bioscience	2 vials	EUR 10340
Description: Recombinant Jurkat T cell expressing firefly luciferase gene under the control of NFAT response elements with constitutive expression of woodchuck (groundhog, Marmota monax) PD-1 (Programmed Cell Death 1, PDCD1, SLEB2, CD279, GenBank Accession #HQ403652)._x000D_

Anti-BCMA CAR Jurkat/NFAT (Luciferase) Reporter Cell Line
79694	BPS Bioscience	2 vials	EUR 9400
Description: The anti-BCMA CAR Jurkat/NFAT-luciferase reporter cell line is a stable cell line made from the anti-BCMA scFV CAR lentivirus (BPS Bioscience #79701). It has been validated for anti BCMA-CAR expression by FACS, and for functional activation stimulated by both soluble BCMA protein (BPS Bioscience #79467) and BCMA/CHO target cells (BPS Bioscience #79500).

PD-1 (Mouse) / NFAT - Reporter - Jurkat Recombinant Cell Line
79762	BPS Bioscience	2 vials	EUR 11095
Description: Recombinant Jurkat T cell expressing firefly luciferase gene under the control of NFAT response elements with constitutive expression of mouse PD-1 (Programmed Cell Death 1, PDCD1, SLEB2, CD279, GenBank Accession #NM_008798).

NFAT Activating Protein With ITAM Motif 1 (NFAM1) Antibody (HRP)
20-abx310130	Abbexa	EUR 493.20 EUR 2214.00 EUR 718.80 EUR 218.40 EUR 360.00	100 ug 1 mg 200 ug 20 ug 50 ug

NFAT Activating Protein With ITAM Motif 1 (NFAM1) Antibody (FITC)
20-abx310131	Abbexa	EUR 493.20 EUR 2214.00 EUR 718.80 EUR 218.40 EUR 360.00	100 ug 1 mg 200 ug 20 ug 50 ug

NFAT Activating Protein With ITAM Motif 1 (NFAM1) Antibody (Biotin)
20-abx310132	Abbexa	EUR 493.20 EUR 2214.00 EUR 718.80 EUR 218.40 EUR 360.00	100 ug 1 mg 200 ug 20 ug 50 ug

Nfam1 ELISA Kit| Mouse NFAT activation molecule 1 ELISA Kit
EF013382	Lifescience Market	96 Tests	EUR 826.8

ADCP Bioassay Effector Cell FcγRIIa (H variant) /NFAT Reporter-Jurkat
71273	BPS Bioscience	2 vials	EUR 6875
Description: Recombinant Jurkat T cell expressing a firefly luciferase gene under the control of NFAT response elements with constitutive expression of human FcγRIIa, Histidine variant.

Growth Arrested PD-1 / NFAT Reporter - Jurkat Recombinant Cell Line
79687	BPS Bioscience	2 vials	EUR 590
Description: Recombinant Jurkat T cell expressing firefly luciferase gene under the control of NFAT response elements with constitutive expression of human PD-1 (Programmed Cell Death 1, PDCD1, SLEB2, CD279, GenBank Accession #NM_005018). Note: These cells are unable to complete mitosis and are suitable for single use assays. For cells capable of reproducing, please use our PD-1 / NFAT Reporter - Jurkat Recombinant Cell Line, #60535.

Anti-CD19 CAR / NFAT (Luciferase) Reporter Jurkat Cell Line (CD19 SCFV-CD28-4-1BB-CD3ζ)
79853	BPS Bioscience	2 vials	EUR 10340
Description: Anti-CD19 CAR/NFAT-luciferase reporter Jurkat cell line is a double stable cell line expressing anti-CD19 CAR and NFAT-luciferase reporter. It is made from the anti-CD19 CAR lentivirus (BPS Bioscience #79851). The reporter cell line has been validated for anti CD19-CAR expression by FACS, and for luciferase reporter activation stimulated by target cells including CD19/CHO recombinant cell line can be used for primary screening and functional validation of anti-CD19 CAR construct and lentivirus before testing in primary T cells. Anti-CD19 CAR consists of anti-CD19 scFv linked to 3rd generation CAR (Chimeric Antigen Receptor) containing CD28, 4-1BB co-stimulatory domains, and CD3ζ signaling domain.

Anti-CD19 CAR negative control/ NFAT (Luciferase) Reporter Jurkat Cell Line (CD19 SCFV-CD28 transmembrane motif)
79854	BPS Bioscience	2 vials	EUR 1650
Description: Anti-CD19 CAR negative control/NFAT-luciferase reporter Jurkat cell line is a double stable cell line expressing anti-CD19 CAR negative control and NFAT-luciferase reporter. The anti-CD19 CAR negative control consists of anti-CD19 scFv linked to the CD28 transmembrane motif without any intracellular signaling domains. The reporter cell line has been validated for anti- CD19 expression by FACS, while the stimulation by target cells including CD19/CHO recombinant cell line has not activated the luciferase reporter gene in this cell line. The cell line can be used for the negative control of anti-CD19 CAR/Jurkat-NFAT cell line (BPS Bioscience, #79853)._x000D_ _x000D_

Consistently higher staining high quality was noticed in slides stained by RabMAb vs MMAb. RabMAb and MMAb towards E-cadherin have been diagnostically equal aside from one case the place RabMAb might have led to diagnostic misinterpretation.

However, the not insignificant value financial savings and simpler interpretation utilizing RabMAb might justify the chance of misinterpretation of elevated staining in uncommon instances, largely avertable with correct coaching.